Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321385 | 0.87 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL10088485 | 0.86 | GRM5 (0.32) | — | |
| SCHEMBL2330276 | 0.82 | PTGS1 (0.44) | PTGS1PTGS2P2RY6P2RY14 | |
| SCHEMBL10088927 | 0.82 | KIF11 (0.39) | PTGS1PTGS2 | |
| SCHEMBL2327128 | 0.80 | ACACB (0.37) | — | |
| SCHEMBL10088499 | 0.80 | NR3C2 (0.30) | — | |
| SCHEMBL10088942 | 0.75 | PDE3B (0.38) | PTGS1PTGS2 | |
| SCHEMBL12440147 | 0.72 | PTPN1 (0.40) | PTGS1PTGS2P2RY6 | |
| SCHEMBL10089047 | 0.72 | MAOA (0.36) | — | |
| SCHEMBL10088904 | 0.70 | SRD5A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2354134-A1 | 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF | Astellas Pharma Inc. (JP) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010064707-A1 | 2H-CHROMENE COMPOUND AND DERIVATIVE THEREOF | アステラス製薬株式会社 (JP) | 2010-06-10 | — | — | WO | disclosed |