Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874349 | 0.81 | DGAT1 (0.43) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL19797961 | 0.80 | TDP1 (0.42) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL30202063 | 0.78 | TDP1 (0.39) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL24074502 | 0.77 | TDP1 (0.36) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL132657 | 0.77 | DGAT1 (0.42) | DGAT1CA12CA14CA2TDP1 | |
| Ammonia Solution, Strong SCHEMBL9998482 | 0.75 | DGAT1 (0.41) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL15064823 | 0.75 | DGAT1 (0.41) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL13857890 | 0.75 | DGAT1 (0.41) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL293062 | 0.74 | CTSK (0.40) | DGAT1CA12CA14CA2TDP1 | |
| SCHEMBL1374814 | 0.74 | DGAT1 (0.52) | DGAT1CA12CA14CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096377-A1 | PYRROLE COMPOUND | 第一三共株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |