Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12441033 | 0.82 | AR (0.46) | ARKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL20602696 | 0.77 | LMNA (0.58) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL12440434 | 0.74 | KDM4E (0.57) | ARKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL12440714 | 0.74 | AR (0.47) | ARKDM4ELMNAGAAHPGD | |
| SCHEMBL6070651 | 0.74 | KMT2A (0.57) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL2358262 | 0.72 | KDM4E (0.68) | ARKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL22529380 | 0.72 | KDM4E (0.63) | ARKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL2360582 | 0.70 | ALOX15 (0.42) | ARLMNAMAPTMEN1KMT2A | |
| SCHEMBL2359348 | 0.69 | AR (0.45) | ARKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL12440855 | 0.68 | AR (0.50) | ARKDM4ELMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531029-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2016-10-19 | — | — | EP | disclosed |
| WO-2011097496-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2011-08-11 | — | — | WO | disclosed |