SCHEMBL12440958

SCHEMBL12440958

CCCCOc1c(C)cc(C)cc1Br

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
L3MBTL1 Q9Y468 3/20 0.59
KDM4E B2RXH2 5/20 0.56
ALDH1A1 P00352 3/20 0.56
LMNA P02545 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
MCL1 Q07820 1/20 0.53
POLB P06746 3/20 0.49
THRA P10827 4/20 0.49
THRB P10828 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.42
HRH3 Q9Y5N1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12440969 0.91 MAPT (0.56) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL12833107 0.90 THRA (0.57) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL11586422 0.86 KMT2A (0.46) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL12440994 0.82 MAPT (0.51) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13144437 0.82 THRA (0.46) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL16330286 0.82 THRA (0.50) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13429866 0.82 THRA (0.46) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13044013 0.81 MAPT (0.46) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL13044016 0.80 MAPT (0.48) MAPTL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL3315111 0.80 THRA (0.48) MAPTL3MBTL1KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAPT 456/4885L3MBTL1 4308/4885KDM4E 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.