SCHEMBL12442183

SCHEMBL12442183

COc1c(C)cc(C(C)(CC(C)C)c2cc(C)c(OC(=O)c3ccc(C=Cc4ccc(C(C)=O)cc4)cc3)c(C)c2)cc1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ TUBB4A P04350 3/20 0.35
▸ TUBB P07437 3/20 0.35
▸ TUBA3C P0DPH7 3/20 0.35
▸ TUBA1B P68363 3/20 0.35
▸ TUBA4A P68366 3/20 0.35
▸ TUBB4B P68371 3/20 0.35
▸ TUBB3 Q13509 3/20 0.35
▸ TUBB2A Q13885 3/20 0.35
▸ TUBB8 Q3ZCM7 3/20 0.35
▸ TUBA3E Q6PEY2 3/20 0.35
▸ TUBA1A Q71U36 3/20 0.35
▸ TUBA1C Q9BQE3 3/20 0.35
▸ TUBB6 Q9BUF5 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12971605 0.94 TUBB4A (0.37) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL12442202 0.90 TUBB4A (0.35) MAPTALDH1A1KMT2AGAASMN1; SMN2
SCHEMBL15756133 0.88 ESR1 (0.34) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL12971606 0.86 KMT2A (0.35) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL13084553 0.86 ALDH1A1 (0.38) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL12925840 0.85 MAPT (0.41) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL12442226 0.84 AAK1 (0.34) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL12925853 0.83 KMT2A (0.43) MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL12925833 0.81 KMT2A (0.43) MAPTKMT2AMEN1SMN1; SMN2
SCHEMBL13084533 0.79 TUBB4A (0.37) MAPTALDH1A1KMT2AGAATUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8568893-B2 Birefringent film and polarizer NITTO DENKO CORPORATION (JP) 2013-10-29 — — US disclosed
US-20110176092-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY NITTO DENKO CORPORATION (JP) 2011-07-21 — — US disclosed
US-20100328772-A1 BIREFRINGENT FILM AND POLARIZER NITTO DENKO CORPORATION (JP) 2010-12-30 — — US disclosed
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