Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 8/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612605 | 0.86 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DOXTR | |
| SCHEMBL13605180 | 0.85 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DOXTR | |
| SCHEMBL16518373 | 0.77 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DOXTR | |
| SCHEMBL16316832 | 0.77 | OXTR (0.38) | OXTRAVPR1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL65381 | 0.77 | ALDH1A1 (0.49) | PDE4APDE4BPDE4CPDE4DOXTR | |
| SCHEMBL17518855 | 0.76 | OXTR (0.50) | OXTRAVPR1AKMT2AALDH1A1GAA | |
| SCHEMBL19724710 | 0.74 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DOXTR | |
| SCHEMBL19724903 | 0.74 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DOXTR | |
| SCHEMBL1344184 | 0.72 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL14276878 | 0.72 | NAMPT (0.45) | KMT2AKDM4EALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190836-B1 | 2-HETEROARYLAMINO-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2011-08-17 | — | — | EP | disclosed |