Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443884 | 0.80 | MAP3K5 (0.63) | MAP3K5CSNK2A1ABCG2ABCB1ABCC1 | |
| SCHEMBL12515414 | 0.79 | MAP3K5 (0.58) | MAP3K5CSNK2A1ABCG2ABCB1ABCC1 | |
| SCHEMBL2219871 | 0.79 | POLB (0.72) | MAP3K5CSNK2A1POLBMAPTNEK2 | |
| SCHEMBL21925740 | 0.77 | MAP3K5 (0.59) | MAP3K5CSNK2A1ABCG2ABCB1ABCC1 | |
| SCHEMBL3246720 | 0.76 | POLB (0.68) | MAP3K5CSNK2A1POLBNEK2JAK2 | |
| SCHEMBL21635739 | 0.75 | RHOA (0.66) | MAP3K5CSNK2A1ABCG2ABCB1ABCC1 | |
| SCHEMBL4683156 | 0.73 | NPC1 (0.54) | MAPTMEN1KMT2ARHOAAURKA | |
| SCHEMBL1934668 | 0.73 | MAPT (0.75) | MAP3K5ABCG2ABCB1ABCC1POLB | |
| SCHEMBL31436022 | 0.73 | MAPT (0.75) | MAP3K5ABCG2ABCB1ABCC1POLB | |
| SCHEMBL16928500 | 0.73 | MAP3K5 (0.54) | MAP3K5CSNK2A1ABCG2ABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110173763-A1 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2011-07-21 | — | — | US | disclosed |
| WO-2009093041-A2 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE F0R DEFENCE (GB) | 2009-07-30 | — | — | WO | disclosed |