Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | NEK2 | P51955 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246720 | 0.97 | POLB (0.68) | POLBMAP3K5NFKB1AURKAAURKB | |
| SCHEMBL13771495 | 0.92 | ALDH1A1 (0.64) | POLBMAP3K5NFKB1AURKAAURKB | |
| SCHEMBL12443884 | 0.86 | MAP3K5 (0.63) | POLBMAP3K5AURKAAURKBALDH1A1 | |
| SCHEMBL3243500 | 0.86 | MAP3K5 (0.60) | POLBMAP3K5AURKAAURKBALDH1A1 | |
| SCHEMBL12515414 | 0.85 | MAP3K5 (0.58) | POLBMAP3K5AURKAAURKBMEN1 | |
| SCHEMBL21925740 | 0.83 | MAP3K5 (0.59) | POLBMAP3K5AURKAAURKBMEN1 | |
| SCHEMBL16928500 | 0.81 | MAP3K5 (0.54) | POLBMAP3K5AURKAAURKBALDH1A1 | |
| SCHEMBL14388020 | 0.81 | POLB (0.93) | POLBNFKB1AURKAMEN1MAPT | |
| SCHEMBL13771598 | 0.80 | POLB (0.48) | POLBMAP3K5NFKB1AURKAAURKB | |
| SCHEMBL20820089 | 0.80 | NFKB1 (0.76) | POLBNFKB1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110173763-A1 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110173763-A1 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2011-07-21 | — | — | US | disclosed |
| US-20110173763-A1 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2011-07-21 | — | — | US | disclosed |
| EP-2235252-A2 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009093041-A2 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE F0R DEFENCE (GB) | 2009-07-30 | — | — | WO | disclosed |