Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.58 |
| ▸ | NEK2 | P51955 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443884 | 0.86 | MAP3K5 (0.63) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL2219871 | 0.85 | POLB (0.72) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL21925740 | 0.83 | MAP3K5 (0.59) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL3246720 | 0.82 | POLB (0.68) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL12443882 | 0.79 | MAP3K5 (0.52) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL16928500 | 0.78 | MAP3K5 (0.54) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL13771495 | 0.78 | ALDH1A1 (0.64) | MAP3K5NEK2POLBCSNK2A1ALDH1A1 | |
| SCHEMBL21635739 | 0.78 | RHOA (0.66) | MAP3K5CSNK2A1ALDH1A1RAB9ACYP1A2 | |
| SCHEMBL1901172 | 0.78 | ALDH1A1 (0.76) | POLBALDH1A1NR4A1RAB9ACYP1A2 | |
| SCHEMBL12443886 | 0.75 | CSNK2A1 (0.48) | MAP3K5NEK2CSNK2A1KITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110173763-A1 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2011-07-21 | — | — | US | disclosed |