Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 11/20 | 0.39 |
| ▸ | CDK9 | P50750 | 11/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.36 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.36 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243760 | 0.88 | PIP4K2C (0.44) | CCNT1CDK9PIP4K2CMCHR1PIP4K2A | |
| SCHEMBL1243768 | 0.86 | PIP4K2C (0.42) | CCNT1CDK9PIP4K2CPIP4K2APIP4K2B | |
| SCHEMBL4372010 | 0.85 | PIP4K2C (0.40) | CCNT1CDK9PIP4K2CCCNA2CDK2 | |
| SCHEMBL28527047 | 0.84 | CCNT1 (0.39) | CCNT1CDK9PIP4K2CCCNA2CDK2 | |
| SCHEMBL20789388 | 0.81 | PIP4K2C (0.40) | CCNT1CDK9PIP4K2CPIP4K2APIP4K2B | |
| SCHEMBL4378684 | 0.81 | PIP4K2C (0.42) | CCNT1CDK9PIP4K2CMCHR1PIP4K2A | |
| SCHEMBL4373806 | 0.81 | CYP2D6 (0.52) | CCNT1CDK9PIP4K2CPIP4K2APIP4K2B | |
| SCHEMBL1244273 | 0.80 | PIP4K2C (0.43) | CCNT1CDK9PIP4K2CPIP4K2APIP4K2B | |
| SCHEMBL1244828 | 0.80 | PIP4K2C (0.42) | CCNT1CDK9PIP4K2CPIP4K2APIP4K2B | |
| SCHEMBL1243624 | 0.80 | PIP4K2C (0.47) | CCNT1CDK9PIP4K2CMCHR1PIP4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879853-B2 | tyrosisne kinase inhibitors such as N-[4-(6-Dibenzofuran-4-yl-pyrimidin-4-ylamino)-phenyl]-4-morpholin-4-yl-benzamide, used as anticasrcinogenic or antoproliferative agents, especially in the treatment of breast cancer | BAYER SCHERING PHARMA AG (DE) | 2011-02-01 | — | — | US | disclosed |
| US-20070208034-A1 | 4,6-disubstituted pyrimidines and their use as protein kinase inhibitors | ATLANTA PHARMA AG (DE) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208034-A1 | 4,6-disubstituted pyrimidines and their use as protein kinase inhibitors | CDK2, DCK, DTYMK | CCNT1 343/4885CDK9 39/4885PIP4K2C 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.