SCHEMBL12445115

SCHEMBL12445115

CCCSC(C)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12834886 0.82
SCHEMBL28342686 0.82 TSHR (0.48)
SCHEMBL7719659 0.78 CES2 (0.45)
SCHEMBL35853 0.78 NOS3 (0.46)
SCHEMBL6959784 0.75
SCHEMBL6965957 0.75
SCHEMBL10915594 0.75
SCHEMBL2029533 0.73
SCHEMBL801912 0.73 NOS3 (0.48)
SCHEMBL7303988 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912594-B2 Carbon disulfide-modified amine additives for separation of oil from water BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2024-02-27 US disclosed
EP-3243909-B1 METHODS FOR PERFORMING HYBRIDIZATIONS WITH SEPARATE DENATURATION OF THE SAMPLE AND PROBE AGILENT TECHNOLOGIES INC (US) 2020-09-02 EP disclosed
EP-2285979-B2 HYBRIDIZATION COMPOSITIONS AND METHODS DAKO DENMARK AS (DK) 2020-02-19 EP disclosed
US-8993697-B2 Conducting and semiconducting organic materials Commonwealth Scientific and Industrial Research Institute Organisation (AU) 2015-03-31 US disclosed
US-20130289217-A1 CONDUCTING AND SEMICONDUCTING ORGANIC MATERIALS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-10-31 US disclosed
US-8501889-B2 Conducting and semiconducting organic materials COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2013-08-06 US disclosed
US-8372860-B2 Carboline derivatives useful in the inhibition of angiogenesis PTC THERAPEUTICS, INC. (US) 2013-02-12 US disclosed
US-8372860-B2 Carboline derivatives useful in the inhibition of angiogenesis PTC THERAPEUTICS, INC. (US) 2013-02-12 US disclosed
US-20110166298-A1 CONDUCTING AND SEMICONDUCTING ORGANIC MATERIALS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL ORGANISATION (AU) 2011-07-07 US disclosed
US-20100179132-A1 CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS PTC THERAPEUTICS, INC. 2010-07-15 US disclosed
US-20100179132-A1 CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS PTC THERAPEUTICS, INC. 2010-07-15 US disclosed
US-20100158858-A1 ADMINISTRATION OF CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISEASES PTC THERAPEUTICS, INC. 2010-06-24 US disclosed
US-7601840-B2 Carboline derivatives useful in the inhibition of angiogenesis PTC THERAPEUTICS, INC. (US) 2009-10-13 US disclosed
US-20090023928-A1 PHTHALAMIDE-LANTHANIDE COMPLEXES FOR USE AS LUMINESCENT MARKERS THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) 2009-01-22 US disclosed
US-20070281962-A2 Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration PCT THERAPEUTICS, INC. (US) 2007-12-06 US disclosed