Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256286 | 0.86 | ALDH1A1 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL9877900 | 0.82 | — | — | |
| SCHEMBL22142804 | 0.82 | — | — | |
| SCHEMBL18725543 | 0.82 | — | — | |
| SCHEMBL25120947 | 0.79 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| SCHEMBL20610005 | 0.76 | TSHR (0.59) | TSHRTDP1 | |
| SCHEMBL19986562 | 0.74 | TSHR (0.46) | TSHR | |
| SCHEMBL17928911 | 0.73 | — | — | |
| SCHEMBL18085391 | 0.73 | — | — | |
| SCHEMBL104640 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098998-A2 | CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2011-08-18 | — | — | WO | disclosed |