⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725543 | 1.00 | — | — | |
| SCHEMBL22142804 | 1.00 | — | — | |
| SCHEMBL2922692 | 0.82 | — | — | |
| SCHEMBL12445587 | 0.82 | TSHR (0.39) | — | |
| SCHEMBL385017 | 0.79 | — | — | |
| SCHEMBL18358834 | 0.79 | — | — | |
| SCHEMBL11835112 | 0.78 | OPRM1 (0.44) | — | |
| SCHEMBL20693661 | 0.78 | OPRM1 (0.44) | — | |
| SCHEMBL8977977 | 0.78 | OPRM1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL1934557 | 0.76 | DNM1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112618728-B | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2022-07-29 | — | — | CN | claimed |
| CN-112618728-A | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2021-04-09 | — | — | CN | claimed |
| US-11718698-B2 | Polyolefin grafted polydiene polymers, and methods of making and using same | BRIDGESTONE CORPORATION (JP) | 2023-08-08 | — | — | US | disclosed |
| EP-3080608-B1 | MASS LABELS | ELECTROPHORETICS LTD (GB) | 2023-02-01 | — | — | EP | disclosed |
| CN-112618728-B | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2022-07-29 | — | — | CN | disclosed |
| US-20210230420-A1 | Polyolefin Grafted Polydiene Polymers, And Methods Of Making And Using Same | BRIDGESTONE CORPORATION (JP) | 2021-07-29 | — | — | US | disclosed |
| CN-112618728-A | Dual-response prodrug containing polysialic acid group, synthetic method thereof and application thereof in pharmaceutical preparation | 绍兴文理学院 | 2021-04-09 | — | — | CN | disclosed |
| EP-3397666-B1 | POLYOLEFIN GRAFTED POLYDIENE POLYMERS, AND METHODS OF MAKING AND USING SAME | BRIDGESTONE CORP (JP) | 2020-08-26 | — | — | EP | disclosed |
| CN-108473635-B | Polyolefin grafted polydiene polymers and methods of making and using the same | 株式会社普利司通 | 2020-08-25 | — | — | CN | disclosed |
| US-10697976-B2 | Mass labels | ELECTROPHORETICS LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-20180362695-A1 | Polyolefin Grafted Polydiene Polymers, And Methods Of Making And Using Same | BRIDGESTONE CORPORATION (JP) | 2018-12-20 | — | — | US | disclosed |
| US-20130143251-A1 | EXPEDITIOUS SYNTHESIS OF UBIQUITINATED PEPTIDE CONJUGATES | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2013-06-06 | — | — | US | disclosed |
| US-20130060003-A1 | CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2013-03-07 | — | — | US | disclosed |
| US-20130041132-A1 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2013-02-14 | — | — | US | disclosed |
| WO-2011098999-A2 | CHEMICAL PREPARATION OF UBIQUITIN THIOESTERS AND MODIFICATIONS THEREOF | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011098998-A2 | CHEMICAL PREPARATION OF POLYUBIQUITIN CHAINS | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2011-08-18 | — | — | WO | disclosed |
| US-4992542-A | Thienamycin antibiotics | MERCK & CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4499103-A | Benzothiazole-2-sulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO., INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0122831-A2 | Benzothiazole-2-sulfonamide derivatives for the topical treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4338419-A | REDUCING IRRITATION FROW WEARING CONTACT LENSES | SYNTEX (U.S.A.) INC. (US) | 1982-07-06 | — | — | US | disclosed |