Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402524 | 0.80 | HTR2B (0.54) | MEN1LMNAKMT2ATDP1HTR2B | |
| SCHEMBL31047805 | 0.80 | KDM4E (0.45) | MEN1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL3341429 | 0.80 | MEN1 (0.42) | MEN1KMT2AGRM5HTR2BCCR1 | |
| SCHEMBL10751660 | 0.80 | IDO1 (0.40) | MEN1LMNAKMT2AHTR2BALDH1A1 | |
| SCHEMBL10752851 | 0.80 | NPC1 (0.42) | TERT | |
| SCHEMBL2089813 | 0.80 | KDM4E (0.45) | MEN1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL10752747 | 0.80 | TERT (0.47) | MEN1KMT2ATDP1ALDH1A1TERT | |
| SCHEMBL10756685 | 0.80 | HSD17B10 (0.42) | LMNAKMT2ATDP1HTR2BALDH1A1 | |
| SCHEMBL29476108 | 0.80 | CCR1 (0.48) | MEN1LMNAKMT2ATDP1ALDH1A1 | |
| SCHEMBL2151538 | 0.80 | CCR1 (0.48) | MEN1LMNAKMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310399-B1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEM PATENTS INC (US) | 2015-04-01 | — | — | EP | disclosed |
| US-7973116-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-07-05 | — | — | US | disclosed |
| US-7973116-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-07-05 | — | — | US | disclosed |
| WO-2010011435-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-01-28 | — | — | WO | disclosed |
| US-20100022726-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2010-01-28 | — | — | US | disclosed |
| US-20100022726-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022726-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | PNPO, NCLN, PARN | MEN1 1585/4885LMNA 2135/4885THRB 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.