Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22488141 | 0.81 | CYP3A4 (0.45) | TDP1CYP3A4SMN1; SMN2KDM4EHTR2A | |
| SCHEMBL49617 | 0.77 | TDP1 (0.38) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| SCHEMBL49367 | 0.77 | TSHR (0.38) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| SCHEMBL30514704 | 0.76 | TDP1 (0.37) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| SCHEMBL4750482 | 0.76 | LTA4H (0.36) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| Hydrochloric Acid SCHEMBL28497176 | 0.76 | TDP1 (0.37) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| SCHEMBL9414101 | 0.76 | TDP1 (0.37) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| SCHEMBL7788089 | 0.76 | TSHR (0.37) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| Hydrochloric Acid SCHEMBL28975804 | 0.76 | TDP1 (0.37) | LTA4HPCSK9TDP1CYP3A4PTGS2 | |
| SCHEMBL10585317 | 0.76 | TDP1 (0.37) | LTA4HPCSK9TDP1CYP3A4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098160-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | ENANTIA, S.L. (ES) | 2011-08-18 | — | — | WO | disclosed |