Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49367 | 0.98 | TSHR (0.38) | TSHRLTA4HPCSK9TDP1CYP3A4 | |
| SCHEMBL7944468 | 0.95 | TSHR (0.37) | TSHRLTA4HPCSK9TDP1CYP3A4 | |
| SCHEMBL11474282 | 0.93 | CES2 (0.37) | TSHRLTA4HPCSK9TDP1CYP3A4 | |
| SCHEMBL6791527 | 0.91 | DNM1 (0.39) | LTA4HSMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL2550792 | 0.91 | LTA4H (0.38) | TSHRLTA4HPCSK9TDP1CYP3A4 | |
| SCHEMBL7788033 | 0.90 | TSHR (0.34) | TSHRLTA4HPCSK9TDP1CYP3A4 | |
| SCHEMBL6288242 | 0.89 | DNM1 (0.40) | LTA4HSMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL15658774 | 0.89 | TSHR (0.36) | TSHRLTA4HPCSK9TDP1CYP3A4 | |
| SCHEMBL3813028 | 0.89 | DNM1 (0.40) | LTA4HSMN1; SMN2SIGMAR1CES2CES1 | |
| SCHEMBL6288656 | 0.89 | DNM1 (0.40) | LTA4HSMN1; SMN2SIGMAR1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834497-B1 | PROCESS FOR PRODUCING 3-ISOCHROMANONES | SAGAMI CHEM RES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5886211-A | Process for producing 2-(halomethyl)phenylacetic acid esters | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0834497-A1 | PROCESS FOR PRODUCING 2-(HALOMETHYL)PHENYLACETIC ACID ESTERS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-08 | — | — | EP | disclosed |