SCHEMBL1244600

SCHEMBL1244600

CC(C)(C)COCCCOCC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GBA2 Q9HCG7 2/20 0.38
CYP2C19 P33261 1/20 0.35
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26016324 0.97 GBA2 (0.37) GBA2CYP2C19CES1
SCHEMBL26016323 0.97 GBA2 (0.37) GBA2CYP2C19CES1
SCHEMBL26016322 0.97 GBA2 (0.37) GBA2CYP2C19CES1
SCHEMBL25939791 0.93 GBA2 (0.42) GBA2CYP2C19CES1
SCHEMBL10287420 0.89 GBA2 (0.34) GBA2
SCHEMBL19420791 0.87 HRH3 (0.41) GBA2
SCHEMBL20314553 0.87 GBA2 (0.33) GBA2
SCHEMBL19420788 0.87 HRH3 (0.41) GBA2
SCHEMBL6377531 0.86 CYP2C19 (0.38) GBA2CYP2C19
SCHEMBL13817758 0.85 HRH3 (0.39) GBA2CYP2C19CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384908-B2 Multilayer polypropylene film for capacitor PRIME POLYMER CO., LTD. (JP) 2025-08-12 US disclosed
CN-115210833-B Multilayer polypropylene film for capacitor 普瑞曼聚合物株式会社 2024-08-13 CN disclosed
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides ARVINAS OPERATIONS, INC. (US) 2024-07-16 US disclosed
EP-3647329-B1 PROPYLENE-BASED POLYMER, METHOD FOR PREPARING SAME, PROPYLENE-BASED RESIN COMPOSITION, AND MOLDED BODY MITSUI CHEMICALS INC (JP) 2024-05-29 EP disclosed
US-11912699-B2 Tau-protein targeting compounds and associated ARVINAS OPERATIONS, INC. (US) 2024-02-27 US disclosed
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2024-01-02 US disclosed
US-11707452-B2 Modulators of alpha-synuclein proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2023-07-25 US disclosed
US-20230088053-A1 MULTILAYER POLYPROPYLENE FILM FOR CAPACITOR PRIME POLYMER CO., LTD. (JP) 2023-03-23 US disclosed
EP-4116997-A1 MULTILAYER POLYPROPYLENE FILM FOR CAPACITOR Prime Polymer Co., Ltd. (JP) 2023-01-11 EP disclosed
CN-110662773-B Propylene polymer, method for producing same, propylene resin composition, and molded article 三井化学株式会社 2022-08-19 CN disclosed
EP-0362705-B1 Catalysts for the polymerization of olefins HIMONT INC (US) 1995-01-11 EP disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
US-4971937-A COORDINATION CATALYSTS OF TITANIUM HALIDES, MAGNESIUM HALIDES AND DI OR POLYETHER COMPOUNDS HIMONT INCORPORATED (US) 1990-11-20 US disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed
EP-0361494-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912699-B2 Tau-protein targeting compounds and associated MAPT, VHL, CRBN GBA2 3172/4885CYP2C19 4879/4885CES1 4218/4885
US-12036209-B2 Compounds and methods for the targeted degradation of Interleukin-1 receptor-associated kinase 4 polypeptides IRAK1, IRAK4, IRAK2 GBA2 4133/4885CYP2C19 4875/4885CES1 2784/4885
US-11707452-B2 Modulators of alpha-synuclein proteolysis and associated methods of use UCHL1, ADRM1, CRBN GBA2 784/4885CYP2C19 4865/4885CES1 3613/4885
US-11858940-B2 Selective modulators of mutant LRRK2 proteolysis and associated methods of use LRRK2, ADRM1, CRBN GBA2 824/4885CYP2C19 4846/4885CES1 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.