Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19434505 | 0.92 | TDP1 (0.46) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL17937439 | 0.92 | TDP1 (0.46) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL22276648 | 0.89 | TDP1 (0.56) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL22276641 | 0.89 | TDP1 (0.56) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL12885084 | 0.89 | TDP1 (0.56) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL21070330 | 0.88 | TDP1 (0.43) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL21070375 | 0.88 | TDP1 (0.43) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL1747780 | 0.88 | TDP1 (0.43) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL21070586 | 0.88 | TDP1 (0.43) | TDP1MEN1KMT2AGAACA12 | |
| SCHEMBL13055393 | 0.88 | TDP1 (0.58) | TDP1MEN1KMT2AGAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482855-B1 | OLIGOMER-CALCIMIMETIC CONJUGATES AND RELATED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2017-12-27 | — | — | EP | disclosed |
| US-9421275-B2 | Oligomer-calcimimetic conjugates and related compunds | NEKTAR THERAPEUTICS (US) | 2016-08-23 | — | — | US | disclosed |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | NEKTAR THERAPEUTICS (US) | 2014-10-30 | — | — | US | disclosed |
| US-8722732-B2 | Oligomer-calcimimetic conjugates and related compounds | NEKTAR THERAPEUTICS (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | NEKTAR THERAPEUTICS (US) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238621-A1 | Oligomer-Calcimimetic Conjugates and Related Compounds | CALCR, CALCB, CALCA | TDP1 3933/4885MEN1 86/4885KMT2A 4536/4885 |
| US-20140323565-A1 | Oligomer-Calcimimetic Conjugates and Related Compunds | CALCR, CALCB, CALCA | TDP1 3636/4885MEN1 70/4885KMT2A 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.