SCHEMBL12447604

SCHEMBL12447604

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc4oc5ccc(-c6cccc7c8ccccc8n(-c8ccccc8)c67)cc5c4c3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
PLA2G10 O15496 1/20 0.38
PRKDC P78527 5/20 0.37
SIRT2 Q8IXJ6 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
BRCA1 P38398 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14296121 0.98 L3MBTL1 (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL14296120 0.98 L3MBTL1 (0.41) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL12447601 0.95 PLA2G2A (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL12447600 0.94 PLA2G2A (0.39) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL12447599 0.93 KDM4E (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL21365490 0.93 PLA2G2A (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL14296049 0.93 KDM4E (0.40) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL21365498 0.92 PLA2G2A (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL12447589 0.92 PLA2G2A (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL12447593 0.91 KDM4E (0.42) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9461250-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-10-04 US disclosed
US-20120235136-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-20 US disclosed
US-20120235136-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-20 US disclosed