Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15233138 | 0.82 | ALDH1A1 (0.41) | MAPTSMN1; SMN2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL16962379 | 0.79 | PDK2 (0.40) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL10777241 | 0.79 | PTGS1 (0.48) | MEN1KMT2ANPC1RAB9APTGS1 | |
| SCHEMBL26477950 | 0.77 | PPARA (0.53) | PPARAPPARG | |
| SCHEMBL12490220 | 0.77 | PTGS1 (0.47) | MEN1KMT2ANPC1RAB9APTGS1 | |
| SCHEMBL16951721 | 0.77 | PDK2 (0.42) | MAPTSMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL11133992 | 0.76 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL16951724 | 0.75 | PDK2 (0.46) | NPC1RAB9AMAPTHSP90AA1TDP1 | |
| SCHEMBL28991434 | 0.75 | CA12 (0.59) | MEN1KMT2ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7737541 | 0.75 | PTGS1 (0.45) | MEN1KMT2ANPC1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568688-B1 | THERAPEUTIC AGENT FOR RESPIRATORY DISEASE CONTAINING 4-HYDROXYPIPERIDINE DERIVATIVE AS ACTIVE INGREDIENT | MOCHIDA PHARM CO LTD (JP) | 2011-08-31 | — | — | EP | disclosed |