Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CAMKK1 | Q8N5S9 | 10/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421308 | 0.80 | CAMKK2 (0.47) | CAMKK2CAMKK1ACMSDNUDT1BACE1 | |
| SCHEMBL10686809 | 0.79 | NUDT1 (0.61) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL9857942 | 0.77 | NUDT1 (0.59) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL12448486 | 0.76 | MEN1 (0.47) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL10917666 | 0.76 | MEN1 (0.43) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL30010714 | 0.76 | CAMKK2 (0.45) | CAMKK2CAMKK1ACMSD | |
| SCHEMBL28029805 | 0.75 | PPARA (0.57) | CAMKK2NUDT1BACE1PPARA | |
| SCHEMBL15006288 | 0.74 | XDH (0.50) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL28427162 | 0.74 | MAPT (0.42) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL21526712 | 0.74 | CAMKK2 (0.40) | CAMKK2CAMKK1ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58041853-A | — | — | None | — | — | JP | disclosed |
| JP-S5841853-A | 4-(4'-TRANS-ALKYLCYCLOHEXYL)BENZOIC ESTERS OF 3-ALKYLOXY- HYDROXY-PHTHALONITRILE | CHISSO CORP | 1983-03-11 | — | — | JP | disclosed |