Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL1245505 | 0.84 | ALOX5 (0.53) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL1243579 | 0.81 | ALOX5 (0.62) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL12727656 | 0.79 | MAPT (0.66) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5278210 | 0.78 | TAAR1 (0.53) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL2628252 | 0.78 | MEN1 (0.66) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL27557266 | 0.78 | MEN1 (0.66) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL29559249 | 0.77 | MEN1 (0.77) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL319385 | 0.77 | MEN1 (0.77) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL319386 | 0.77 | MEN1 (0.77) | ALOX5EPHX2MAPTMEN1KMT2A | |
| SCHEMBL1246644 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459733-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | claimed |
| US-8535902-B2 | Peptidase substrates | bioMërieux, S.A. | 2013-09-17 | — | — | US | claimed |
| EP-2459733-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | claimed |
| US-20120129203-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-24 | — | — | US | claimed |
| WO-2011012807-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | claimed |
| EP-2459733-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8535902-B2 | Peptidase substrates | bioMërieux, S.A. | 2013-09-17 | — | — | US | disclosed |
| EP-2459733-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| US-20120129203-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-24 | — | — | US | disclosed |
| WO-2011012807-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129203-A1 | Novel Peptidase Substrates | CTRL, CPB1, ANPEP | ALOX5 568/4885EPHX2 624/4885MAPT 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.