Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548162 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL80731 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL14130407 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL80732 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL13559128 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL18271744 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL14130644 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL12521907 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL13619173 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 | |
| SCHEMBL725337 | 1.00 | TRPA1 (0.43) | TRPA1TRPM8GBA1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9320705-B2 | Sensation modifying topical composition foam | FOAMIX PHARMACEUTICALS LTD. (IL) | 2016-04-26 | — | — | US | disclosed |
| US-20120237453-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | FOAMIX LTD. (IL) | 2012-09-20 | — | — | US | disclosed |
| EP-1567013-B1 | ACETALS AS INSECT REPELLANT AGENTS | BENCSITS FRANZ (AT) | 2007-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120237453-A1 | SENSATION MODIFYING TOPICAL COMPOSITION FOAM | TRPA1, GPR35, TRPV1 | TRPA1 1/4885TRPM8 6/4885GBA1 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.