SCHEMBL12449846

SCHEMBL12449846

Bc1cc(Br)c2oc3ccccc3c2c1N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC14B O60729 1/20 0.41
CDC14A Q9UNH5 1/20 0.41
KDM4E B2RXH2 5/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 4/20 0.38
MEN1 O00255 4/20 0.38
MAPT P10636 4/20 0.38
KMT2A Q03164 4/20 0.38
GAA P10253 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
NQO1 P15559 1/20 0.38
LIMK1 P53667 1/20 0.36
PTPRC P08575 1/20 0.35
PTPRF P10586 1/20 0.35
PTPN1 P18031 1/20 0.35
PTPRA P18433 1/20 0.35
PTPRB P23467 1/20 0.35
PTPN6 P29350 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2343971 0.85 CDC14B (0.43) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL26450498 0.81 CDC14B (0.44) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL2341671 0.76 CASP6 (0.43) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL26450552 0.75 CDC14B (0.44) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL18086413 0.75 L3MBTL1 (0.46) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL21032599 0.75 CDC14B (0.46) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL9106395 0.75 AHR (0.47) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL22171918 0.75 CDC14B (0.46) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL28525740 0.73 CDC14B (0.51) CDC14BCDC14AKDM4EALDH1A1HPGD
SCHEMBL30152055 0.72 CDC14B (0.56) CDC14BCDC14AKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110204333-A1 PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110204333-A1 PHOSPHORESCENT EMITTERS TEC, IK, DDT CDC14B 2431/4885CDC14A 2367/4885KDM4E 2260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.