Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15493550 | 0.83 | KMT2A (0.33) | KMT2AP2RY12 | |
| SCHEMBL12629144 | 0.78 | KMT2A (0.47) | KMT2ASCN9ASCN10AWNT1GSK3B | |
| SCHEMBL12522433 | 0.78 | HRH1 (0.33) | SCN9A | |
| SCHEMBL12629018 | 0.74 | KMT2A (0.44) | KMT2ASCN9ASCN10AKDM4EALDH1A1 | |
| SCHEMBL21427218 | 0.74 | KMT2A (0.41) | KMT2ASCN9ASCN10AKDM4EALDH1A1 | |
| SCHEMBL21766563 | 0.72 | DRD2 (0.44) | KMT2AALDH1A1DRD2 | |
| SCHEMBL9269191 | 0.72 | KMT2A (0.39) | KMT2ASCN9ASCN10AWNT1GSK3B | |
| SCHEMBL12450078 | 0.71 | HRH1 (0.32) | SCN9A | |
| SCHEMBL12342818 | 0.68 | ALDH1A1 (0.49) | KMT2AKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12693934 | 0.68 | KMT2A (0.40) | KMT2ASCN9ASCN10AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187690-B2 | Rare earth metal complex having phenanthroline compound as ligand | B.R.A.H.M.S. GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-20140058073-A1 | RARE EARTH METAL COMPLEX HAVING PHENANTHROLINE COMPOUND AS LIGAND | B.R.A.H.M.S. GMBH (DE) | 2014-02-27 | — | — | US | disclosed |
| US-8648194-B2 | Compounds having phenanthroline structure | B.R.A.H.M.S GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20120238748-A1 | NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE | B.R.A.H.M.S GMBH (DE) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238748-A1 | NOVEL COMPOUNDS HAVING PHENANTHROLINE STRUCTURE | PAH, BPTF, HDAC1 | KMT2A 506/4885SCN9A 2701/4885SCN10A 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.