Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15718695 | 0.82 | — | — | |
| SCHEMBL5858592 | 0.79 | — | — | |
| SCHEMBL5293916 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL8394291 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL197294 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL27681950 | 0.74 | LMNA (0.40) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL11411261 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL13178076 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL15173697 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| Hydrochloric Acid SCHEMBL11371382 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KMT2ALMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | claimed |
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | disclosed |