Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126139 | 1.00 | TSHR (0.38) | TSHRHSD17B10TDP1LMNAALDH1A1 | |
| SCHEMBL122838 | 1.00 | TSHR (0.38) | TSHRHSD17B10TDP1LMNAALDH1A1 | |
| SCHEMBL110741 | 0.95 | — | — | |
| SCHEMBL15905910 | 0.89 | SPHK1 (0.32) | TSHR | |
| SCHEMBL16675541 | 0.86 | TSHR (0.37) | TSHRTDP1ALDH1A1 | |
| SCHEMBL28576046 | 0.86 | TSHR (0.38) | TSHRTDP1LMNA | |
| SCHEMBL16153750 | 0.86 | TSHR (0.38) | TSHRTDP1LMNA | |
| SCHEMBL3096199 | 0.86 | TSHR (0.38) | TSHRTDP1LMNA | |
| SCHEMBL3096192 | 0.86 | TSHR (0.38) | TSHRTDP1LMNA | |
| SCHEMBL9817472 | 0.85 | GPR84 (0.38) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679537-B2 | Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive | Actamaz Surgical Materials, LLC (US) | 2014-03-25 | — | — | US | disclosed |
| US-8679536-B2 | Aldol-crosslinked polymeric hydrogel adhesives | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2014-03-25 | — | — | US | disclosed |
| EP-2246032-B1 | Process for colouring and/or bleaching hair using a composition comprising an amino trialkoxysilane | OREAL (FR) | 2013-11-20 | — | — | EP | disclosed |
| EP-2266528-B1 | Process for colouring and/or bleaching human hair using a composition comprising an amino trialkoxysilane | OREAL (FR) | 2013-09-11 | — | — | EP | disclosed |
| EP-2214632-B1 | LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND | OREAL (FR) | 2012-03-07 | — | — | EP | disclosed |
| US-8029577-B2 | Lightening and/or dyeing of human keratin fibres via a composition comprising a particular amino silicon compound and composition and device | L'OREAL S.A. (FR) | 2011-10-04 | — | — | US | disclosed |
| EP-2266528-A1 | Process for colouring and/or bleaching human hair using a composition comprising an amino trialkoxysilane or amino trialcenyloxysilane | L'Oréal (FR) | 2010-12-29 | — | — | EP | disclosed |
| US-20100297049-A1 | LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE | L'OREAL S.A. (FR) | 2010-11-25 | — | — | US | disclosed |
| EP-2246032-A1 | Process for colouring and/or bleaching hair using a composition comprising an amino trialkoxysilane or amino trialcenyloxysilane | L'Oréal (FR) | 2010-11-03 | — | — | EP | disclosed |