Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122838 | 0.89 | TSHR (0.38) | TSHR | |
| SCHEMBL124516 | 0.89 | TSHR (0.38) | TSHR | |
| SCHEMBL126139 | 0.89 | TSHR (0.38) | TSHR | |
| SCHEMBL110741 | 0.84 | — | — | |
| SCHEMBL15031022 | 0.80 | TSHR (0.41) | TSHR | |
| SCHEMBL21374119 | 0.80 | ALDH1A1 (0.38) | SPHK1METAP1TSHRGRIK1SLC1A3 | |
| SCHEMBL7011297 | 0.80 | ALDH1A1 (0.38) | SPHK1METAP1TSHRGRIK1SLC1A3 | |
| SCHEMBL28374323 | 0.78 | GRIK1 (0.34) | SPHK1METAP1GRIK1SLC1A3SLC1A2 | |
| SCHEMBL16675541 | 0.77 | TSHR (0.37) | TSHR | |
| SCHEMBL16153750 | 0.76 | TSHR (0.38) | TSHRGRIK1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8790632-B2 | Polymer-based tissue-adhesive form medical use | ACTAMAX SURGICAL MATERIALS, LLC (US) | 2014-07-29 | — | — | US | disclosed |