Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CETP | P11597 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.46 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12451634 | 0.87 | PLA2G4A (0.41) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL17804033 | 0.85 | PLA2G4A (0.48) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL6410388 | 0.83 | MAPT (0.74) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL6410392 | 0.83 | MAPT (0.74) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL10025150 | 0.83 | MAPT (0.74) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL6419171 | 0.83 | MAPT (0.74) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL315529 | 0.83 | MAPT (0.74) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL12451652 | 0.83 | MAPT (0.74) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL16581551 | 0.78 | MAPT (0.54) | MAPTTP53CYP2D6MAPK1CYP1A2 | |
| SCHEMBL16586850 | 0.78 | MAPT (0.54) | MAPTTP53CYP2D6MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359389-B2 | Caged ceramide-1-phosphate derivatives | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-06-07 | — | — | US | disclosed |
| US-20120238018-A1 | Caged Ceramide-1-Phosphate Derivatives | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2012-09-20 | — | — | US | disclosed |
| WO-2011056599-A2 | CAGED CERAMIDE-1-PHOSPHATE DERIVATIVES | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238018-A1 | Caged Ceramide-1-Phosphate Derivatives | CERT1, SGMS1, CERS2 | MAPT 2333/4885TP53 2551/4885CYP2D6 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.