Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941659 | 0.86 | PLA2G4A (0.60) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL15948851 | 0.86 | PLA2G4A (0.60) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL12451647 | 0.85 | MAPT (0.51) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL12451634 | 0.85 | PLA2G4A (0.41) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL15887073 | 0.75 | PLA2G4A (0.47) | PLA2G4ATP53CYP1A2CYP2D6MAPT | |
| SCHEMBL17522133 | 0.74 | PLA2G4A (0.46) | PLA2G4A | |
| SCHEMBL10025150 | 0.70 | MAPT (0.74) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL20830129 | 0.70 | CA1 (0.40) | PLA2G4ACYP2D6SMPD1 | |
| SCHEMBL6419171 | 0.70 | MAPT (0.74) | TP53CYP1A2CYP2D6MAPTCYP2C9 | |
| SCHEMBL6410388 | 0.70 | MAPT (0.74) | TP53CYP1A2CYP2D6MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359389-B2 | Caged ceramide-1-phosphate derivatives | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2016-06-07 | — | — | US | disclosed |