Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL1078154 | 1.00 | L3MBTL1 (0.45) | L3MBTL1PTGS1TDP1ALDH1A1LMNA | |
| Toluene SCHEMBL1245378 | 1.00 | L3MBTL1 (0.45) | L3MBTL1PTGS1TDP1ALDH1A1LMNA | |
| Toluene SCHEMBL7782221 | 1.00 | L3MBTL1 (0.45) | L3MBTL1PTGS1TDP1ALDH1A1LMNA | |
| Toluene SCHEMBL1079482 | 0.83 | L3MBTL1 (0.41) | L3MBTL1TDP1ALDH1A1LMNASMN1; SMN2 | |
| Toluene SCHEMBL1159746 | 0.83 | L3MBTL1 (0.41) | L3MBTL1TDP1ALDH1A1LMNASMN1; SMN2 | |
| Toluene SCHEMBL8907280 | 0.83 | L3MBTL1 (0.41) | L3MBTL1TDP1ALDH1A1LMNASMN1; SMN2 | |
| Toluene SCHEMBL8994440 | 0.83 | L3MBTL1 (0.41) | L3MBTL1TDP1ALDH1A1LMNASMN1; SMN2 | |
| Toluene SCHEMBL9293029 | 0.80 | L3MBTL1 (0.40) | L3MBTL1PTGS1TDP1ALDH1A1LMNA | |
| Toluene SCHEMBL2053140 | 0.80 | L3MBTL1 (0.58) | L3MBTL1PTGS1TDP1LMNATSHR | |
| Toluene SCHEMBL1118344 | 0.80 | L3MBTL1 (0.58) | L3MBTL1PTGS1TDP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464359-A2 | N-SULFATED OLIGOSACCHARIDES ACTIVATING FGFS RECEPTORS, THEIR SYNTHESIS AND THEIR THERAPEUTICAL APPLICATION | SANOFI (FR) | 2012-06-20 | — | — | EP | disclosed |
| WO-2011018587-A2 | FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-02-17 | — | — | WO | disclosed |