Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL8994440 | 1.00 | L3MBTL1 (0.41) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| Toluene SCHEMBL8907280 | 1.00 | L3MBTL1 (0.41) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| Toluene SCHEMBL1159746 | 1.00 | L3MBTL1 (0.41) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL7789892 | 0.90 | POLB (0.42) | L3MBTL1TDP1LMNAMEN1KMT2A | |
| SCHEMBL2332010 | 0.85 | SLC22A12 (0.44) | TDP1SMN1; SMN2LMNAMEN1KMT2A | |
| Toluene SCHEMBL1245378 | 0.83 | L3MBTL1 (0.45) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| Toluene SCHEMBL7782221 | 0.83 | L3MBTL1 (0.45) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| Toluene SCHEMBL1245372 | 0.83 | L3MBTL1 (0.45) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| Toluene SCHEMBL1078154 | 0.83 | L3MBTL1 (0.45) | L3MBTL1TDP1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL210161 | 0.81 | PKM (0.42) | L3MBTL1LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11311423-B2 | Facial patch | NICHIBAN CO., LTD. (JP) | 2022-04-26 | — | — | US | disclosed |
| CN-104955426-B | Patch containing clobetasol for treating eyelid diseases | 千寿美国公司 | 2019-01-11 | — | — | CN | disclosed |
| EP-2937066-B1 | FACIAL PATCH | NICHIBAN KK (JP) | 2018-04-25 | — | — | EP | disclosed |
| EP-2934403-B1 | PATCH FOR TREATMENT OF EYELID DISEASES CONTAINING CLOBETASOL | SENJU USA INC (US) | 2018-03-21 | — | — | EP | disclosed |
| US-9211397-B2 | Patch for treatment of eyelid disease containing clobetasol | SENJU USA, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150320606-A1 | Facial Patch | NICHIBAN CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-2937066-A1 | FACIAL PATCH | Nichiban Co. Ltd. (JP) | 2015-10-28 | — | — | EP | disclosed |
| EP-2934403-A2 | PATCH FOR TREATMENT OF EYELID DISEASES CONTAINING CLOBETASOL | SENJU USA, INC. (US) | 2015-10-28 | — | — | EP | disclosed |
| CN-104955426-A | Patch containing clobetasol for treating eyelid diseases | SENJU USA INC | 2015-09-30 | — | — | CN | disclosed |
| WO-2014099894-A2 | PATCH FOR TREATMENT OF EYELID DISEASES CONTAINING CLOBETASOL | SENJU USA, INC. (US) | 2014-06-26 | — | — | WO | disclosed |
| CN-1235908-C | 16,17-carbocyclic condensed steroid compounds having seletive estrogenic activeity | AKZO NOBEL NV (NL) | 2006-01-11 | — | — | CN | disclosed |
| EP-1294739-B1 | 16,17-CARBOCYCLIC CONDENSED STEROID COMPOUNDS HAVING SELECTIVE ESTROGENIC ACTIVITY | AKZO NOBEL NV (NL) | 2005-04-13 | — | — | EP | disclosed |
| US-20040102426-A1 | 16,17-carbocyclic condensed steroid compounds having selective estrogenic activity | MERCK SHARP & DOHME B.V. (NL) | 2004-05-27 | — | — | US | disclosed |
| CN-1433426-A | 16,17-carbocyclic condensed steroid compounds having seletive estrogenic activeity | AKZO NOBEL NV (NL) | 2003-07-30 | — | — | CN | disclosed |
| EP-1294739-A1 | 16,17-CARBOCYCLIC CONDENSED STEROID COMPOUNDS HAVING SELECTIVE ESTROGENIC ACTIVITY | Akzo Nobel N.V. (NL) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000682-A1 | 16, 17-CARBOCYCLIC CONDENSED STEROID COMPOUNDS HAVING SELECTIVE ESTROGENIC ACTIVITY | AKZO NOBEL N.V. (NL) | 2002-01-03 | — | — | WO | disclosed |
| US-6017556-A | PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-01-25 | — | — | US | disclosed |
| US-5352684-A | Antitumor, anticarcinogenic agents | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-10-04 | — | — | US | disclosed |
| US-4965283-A | Anticonvillsants, antiepileptic agents | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4943568-A | Cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102426-A1 | 16,17-carbocyclic condensed steroid compounds having selective estrogenic activity | ESR2, HSD17B11, ESRRA | L3MBTL1 2767/4885TDP1 4595/4885SMN1; SMN2 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.