⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074984 | 1.00 | — | — | |
| SCHEMBL12438 | 0.97 | HRH3 (0.48) | — | |
| SCHEMBL5001162 | 0.97 | HRH3 (0.48) | — | |
| SCHEMBL13174 | 0.97 | HRH3 (0.48) | — | |
| SCHEMBL19909612 | 0.97 | HRH3 (0.48) | — | |
| SCHEMBL1220049 | 0.94 | — | — | |
| SCHEMBL17525470 | 0.91 | HRH3 (0.48) | — | |
| SCHEMBL14844865 | 0.89 | POLB (0.40) | — | |
| SCHEMBL9958336 | 0.89 | HRH3 (0.41) | — | |
| SCHEMBL8149011 | 0.88 | HSD11B1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | VORONOI INC. (KR) | 2024-07-25 | — | — | US | claimed |
| CN-116845349-A | Ion gel electrolyte with stable interface, preparation method and application thereof | 北京理工大学 | 2023-10-03 | — | — | CN | claimed |
| CN-114705247-B | Ion type capacitive pressure and temperature sensing fiber device capable of being manufactured in batch and preparation method thereof | 杭州师范大学 | 2023-09-22 | — | — | CN | claimed |
| CN-111834048-B | Preparation method of multifunctional flexible transparent sensing material based on ionic liquid | 杭州师范大学 | 2022-08-05 | — | — | CN | claimed |
| CN-114705247-A | Novel ion type capacitive pressure and temperature sensing fiber device capable of being manufactured in batch and preparation method thereof | 杭州师范大学 | 2022-07-05 | — | — | CN | claimed |
| CN-112321862-A | Simple process for high-transparency multifunctional ultrathin ionized skin | 杭州师范大学 | 2021-02-05 | — | — | CN | claimed |
| US-7868022-B2 | 2-amino-quinoline derivatives useful as inhibitors of β-secretase (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-11 | — | — | US | claimed |
| EP-1278735-B1 | 2,4-DI(HETERO-)ARYLAMINO(-OXY)-5-SUBSTITUTED PYRIMIDINES AS ANTINEOPLASTIC AGENTS | ASTRAZENECA AB (SE) | 2010-06-30 | — | — | EP | claimed |
| US-20080194624-A1 | 2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE) | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-14 | — | — | US | claimed |
| WO-2007092854-A2 | 2-AMINO-QUINOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE) | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-16 | — | — | WO | claimed |
| US-20050090515-A1 | 2,4,DI (hetero-) arylamino (-oxy) -5-substituted pyrimidines as antineoplastic agents | ASTRAZENECA AB | 2005-04-28 | — | — | US | claimed |
| US-6838464-B2 | 2,4-Di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineaoplastic agents | ASTRAZENECA AB (SE) | 2005-01-04 | — | — | US | claimed |
| US-6653313-B2 | For treatment and prevention of inflammation, asthma, allergic rhinitis, pain and other disorders | WARNER-LAMBERT COMPANY LLC | 2003-11-25 | — | — | US | claimed |
| US-20030181474-A1 | 2,4-Di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineoplastic agents | ASTRAZENECA AB (SE) | 2003-09-25 | — | — | US | claimed |
| EP-1307449-A1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-05-07 | — | — | EP | claimed |
| US-20020161006-A1 | 1,4-dihydropyridine compounds as bradykinin antagonists | KAWAMURA MITSUHIRO (US) | 2002-10-31 | — | — | US | claimed |
| WO-2002012235-A1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-02-14 | — | — | WO | claimed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-4311618-A | Cleanser with ionic and nonionic surfactants | SCHAEFER BURKHARD WERNER | 1982-01-19 | — | — | US | claimed |