Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3142503 | 0.98 | HRH3 (0.39) | HRH3ALDH1A1TDP1POLBPSMB1 | |
| SCHEMBL14844865 | 0.96 | POLB (0.40) | HRH3ALDH1A1TDP1POLBKDM4E | |
| SCHEMBL19909612 | 0.91 | HRH3 (0.48) | HRH3ALDH1A1TDP1POLBPSMB1 | |
| SCHEMBL5001162 | 0.91 | HRH3 (0.48) | HRH3ALDH1A1TDP1POLBPSMB1 | |
| SCHEMBL12438 | 0.91 | HRH3 (0.48) | HRH3ALDH1A1TDP1POLBPSMB1 | |
| SCHEMBL13174 | 0.91 | HRH3 (0.48) | HRH3ALDH1A1TDP1POLBPSMB1 | |
| SCHEMBL12454 | 0.89 | — | — | |
| SCHEMBL2074984 | 0.89 | — | — | |
| SCHEMBL1220049 | 0.84 | — | — | |
| SCHEMBL3152433 | 0.83 | HSD11B1 (0.39) | HRH3ALDH1A1KDM4ELTA4HMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867650-B1 | HYDROXYMETHYLBORON COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |