Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL28251629 | 1.00 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL359821 | 1.00 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL29707583 | 0.95 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL181413 | 0.95 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL181872 | 0.95 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL2254618 | 0.93 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL7038038 | 0.89 | FFAR3 (0.52) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL10901312 | 0.87 | FFAR3 (0.68) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL8159821 | 0.87 | FFAR3 (0.68) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL4578587 | 0.87 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260102368-A1 | NOVEL FEED ADDITIVES COMPRISING FATTY ACID ESTERS AND RELATED METHODS TO IMPROVE ANIMAL GROWTH PERFORMANCE AND HEALTH | KEMIN INDUSTRIES, INC. (US) | 2026-04-16 | — | — | US | claimed |
| CN-113980252-B | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2023-09-01 | — | — | CN | claimed |
| CN-113980252-A | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2022-01-28 | — | — | CN | claimed |
| CN-106873309-A | A kind of Positive photosensitive water solubility dry film solder mask and purposes | 浙江福斯特新材料研究院有限公司 | 2017-06-20 | — | — | CN | claimed |
| US-9470978-B2 | Solution composition for passivation layer, thin film transistor array panel, and manufacturing method for thin film transistor array panel | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-10-18 | — | — | US | claimed |
| CN-105542124-A | Alkaline-water soluble light-cured resin and preparation method thereof | SHENZHEN RONGDA PHOTOSENSITIVE SCIENCE & TECH CO LTD | 2016-05-04 | — | — | CN | claimed |
| US-9188867-B2 | Solution composition for passivation layer, thin film transistor array panel, and manufacturing method for thin film transistor array panel | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-11-17 | — | — | US | claimed |
| US-20150050597-A1 | SOLUTION COMPOSITION FOR PASSIVATION LAYER, THIN FILM TRANSISTOR ARRAY PANEL, AND MANUFACTURING METHOD FOR THIN FILM TRANSISTOR ARRAY PANEL | SAMSUNG DISPLAY CO LTD (KR) | 2015-02-19 | — | — | US | claimed |
| US-8592621-B2 | Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease | SYMRISE AG (DE) | 2013-11-26 | — | — | US | claimed |
| US-20130099228-A1 | SOLUTION COMPOSITION FOR PASSIVATION LAYER, THIN FILM TRANSISTOR ARRAY PANEL, AND MANUFACTURING METHOD FOR THIN FILM TRANSISTOR ARRAY PANEL | SAMSUNG DISPLAY CO., LTD. (KR) | 2013-04-25 | — | — | US | claimed |
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | SYMRISE GMBH CO. KG (DE) | 2011-02-24 | — | — | US | claimed |
| US-20260102368-A1 | NOVEL FEED ADDITIVES COMPRISING FATTY ACID ESTERS AND RELATED METHODS TO IMPROVE ANIMAL GROWTH PERFORMANCE AND HEALTH | KEMIN INDUSTRIES, INC. (US) | 2026-04-16 | — | — | US | disclosed |
| EP-4633581-A1 | A TOPICAL COMPOSITION | Rock & Herb Pte Ltd (SG) | 2025-10-22 | — | — | EP | disclosed |
| US-20240410055-A1 | METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS | MERCK PATENT GMBH (DE) | 2024-12-12 | — | — | US | disclosed |
| US-20240277012-A1 | DUPLICATE BEVERAGE | WANG JIE (US) | 2024-08-22 | — | — | US | disclosed |
| US-5504068-A | DISSOLVED IN ORGANIC SOLVENT WITH A SKIN PENETRATION ENHANCER CONSISTING OF ALKANOLAMINES AND MONOVALENT ALCOHOL ESTERS OF MYRISTIC, ADIPIC AND SEBACIC ACIDS | LTT INSTITUTE CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0615520-A1 | OPTICALLY ACTIVE LACTONES | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0547229-A1 | EXTERNAL PREPARATION CONTAINING CYCLOSPORIN | LTT INSTITUTE CO., LTD. (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-4808443-A | COATING THIN FILM ON WET SURFACE RIGHT AFTER PRINTING | SAKATA SHOKAI, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0063037-B1 | ADHESIVE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260102368-A1 | NOVEL FEED ADDITIVES COMPRISING FATTY ACID ESTERS AND RELATED METHODS TO IMPROVE ANIMAL GROWTH PERFORMANCE AND HEALTH | FABP2, VIP, SLC27A2 | FFAR3 24/4885HDAC3 2730/4885HDAC1 3116/4885 |
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | TAS1R2, TAS2R5, TAS2R1 | FFAR3 163/4885HDAC3 2442/4885HDAC1 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.