SCHEMBL124582

SCHEMBL124582

O=C(O)CN(O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 2/20 0.43
TSHR P16473 2/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
GLA P06280 1/20 0.43
AKR1B1 P15121 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSP90AA1 P07900 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743711 1.00 NPSR1 (0.46) NPSR1TDP1ALDH1A1KMT2ATSHR
Hydrochloric Acid SCHEMBL9194071 0.98 NPSR1 (0.44) NPSR1TDP1ALDH1A1KMT2ATSHR
Ethylene SCHEMBL973759 0.96 NPSR1 (0.43) NPSR1TDP1ALDH1A1KMT2ATSHR
Sulfuric Acid SCHEMBL9324944 0.92 HSP90AA1 (0.43) NPSR1TDP1ALDH1A1KMT2ATSHR
Benzene SCHEMBL28328871 0.87 TSHR (0.43) ALDH1A1TSHRGLASMN1; SMN2HSP90AA1
SCHEMBL28550181 0.87 ALDH1A1 (0.42) NPSR1TDP1ALDH1A1KMT2ATSHR
SCHEMBL9874763 0.85 TSHR (0.55) ALDH1A1KMT2ATSHRPOLBSMN1; SMN2
SCHEMBL28315420 0.84 NPSR1 (0.44) NPSR1TDP1ALDH1A1KMT2ATSHR
SCHEMBL29602588 0.82 ALDH1A1 (0.45) NPSR1TDP1ALDH1A1KMT2ATSHR
SCHEMBL11144520 0.82 NPSR1 (0.43) NPSR1TDP1ALDH1A1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1043 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431171-A Production method of L-p-hydroxyphenylglycine methyl ester 山东优盈新材料有限公司 2025-02-14 CN claimed
CN-119350197-A Continuous process for preparing D-p-hydroxyphenylglycine double salt 浙江沙星科技股份有限公司 2025-01-24 CN claimed
CN-119330894-A Method for synthesizing HO-EPCP by catalyzing DMAP 山东鑫泉医药有限公司 2025-01-21 CN claimed
CN-119198790-A Parhydroxyphenylglycine fermentation enzyme sample detection device 上海邦林生物科技有限公司 2024-12-27 CN claimed
CN-118878433-A Preparation method of D (-) p-hydroxyphenylglycine methyl ester hydrochloride 浙江昂利康制药股份有限公司 2024-11-01 CN claimed
CN-116196980-B Ionic liquid modified epoxy resin-based immobilized metal salt catalyst, and preparation method and application thereof 天津市职业大学 2024-07-05 CN claimed
CN-118010856-A Method for detecting content of D-p-hydroxyphenylglycine 湖北省宏源药业科技股份有限公司 2024-05-10 CN claimed
CN-117999357-A Method for detecting cell stress 波士顿大学董事会 2024-05-07 CN claimed
CN-113636948-B DL-p-hydroxyphenylglycine asymmetric conversion resolution waste liquid treatment method 湖北省宏源药业科技股份有限公司 2024-04-09 CN claimed
CN-117720427-A Recovery processing method of D-p-hydroxyphenylglycine methyl ester mother liquor 山西双雁生物科技有限公司 2024-03-19 CN claimed
EP-0437058-A1 Formation of hydroxyaromatic ketoacetal from an hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and D-p-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1991-07-17 EP claimed
WO-1991009020-A2 PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE HOECHST CELANESE CORPORATION (US) 1991-06-27 WO claimed
US-4810259-A CHELATING AGENT OXCE FUEL COMPANY (US) 1989-03-07 US claimed
EP-0180276-A1 Dioxaphosphorinanes, their preparation and use for resolving optically active compounds STAMICARBON B.V. (NL) 1986-05-07 EP claimed
EP-0070114-B1 A PROCESS FOR PREPARING AN OPTICALLY ACTIVE P-HYDROXYPHENYL-GLYCINE OR A SALT THEREOF Tanabe Seiyaku Co., Ltd. (JP) 1985-06-26 EP claimed
EP-0075318-A2 p-Hydroxyphenylglycine alpha-phenylethanesulfonate, process for production thereof and utilization thereof in resolution of p-hydroxyphenylglycine Tanabe Seiyaku Co., Ltd. (JP) 1983-03-30 EP claimed
US-4369146-A Method for chlorinating the carboxylic group of α-aminoacids CHIMICA BULCIAGO S.R.L. (IT) 1983-01-18 US claimed
US-4205185-A Process for preparing racemic 4-hydroxyphenylglycine STERLING DRUG INC. (US) 1980-05-27 US claimed
US-4175206-A Process for preparing a hydroxyphenylglycine compound TANABE SEIYAKU CO., LTD. (JP) 1979-11-20 US claimed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 US claimed