Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392839 | 1.00 | MGAM (0.59) | MGAMPSMD14KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7010614 | 0.98 | MGAM (0.57) | MGAMPSMD14KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9378228 | 0.98 | MGAM (0.57) | MGAMPSMD14KDM4EMEN1KMT2A | |
| Water SCHEMBL8227338 | 0.89 | ACP1 (0.51) | MGAMPSMD14KDM4EMEN1KMT2A | |
| SCHEMBL28015646 | 0.86 | PSMD14 (0.47) | MGAMPSMD14KDM4EMEN1KMT2A | |
| SCHEMBL27501111 | 0.85 | MGAM (0.79) | MGAMPSMD14KDM4EMEN1KMT2A | |
| SCHEMBL163182 | 0.84 | PSMD14 (0.56) | MGAMPSMD14KDM4EMEN1KMT2A | |
| Aspartic Acid SCHEMBL27878589 | 0.84 | MGAM (0.43) | MGAMPSMD14KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14966721 | 0.83 | PSMD14 (0.55) | MGAMPSMD14KDM4EMEN1KMT2A | |
| SCHEMBL21358078 | 0.83 | PSMD14 (0.60) | MGAMPSMD14KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825756-A | Substituted polycyclic carboxylic acids, analogs thereof, and methods of use thereof | 爱彼特生物制药公司 | 2021-12-21 | — | — | CN | claimed |
| CN-110475777-A | For treating and preventing new pyrido [2,3-b] benzazolyl compounds of bacterium infection | HOFFMANN LA ROCHE | 2019-11-19 | — | — | CN | claimed |
| CN-107286182-A | Novel oxazolidinone fluoro quinolone derivative and purposes | 李靖 | 2017-10-24 | — | — | CN | claimed |
| CN-106632317-A | 1,4-dihydro-naphthyridine derivative and pharmaceutical composition and application thereof | 江苏欧威医药有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104203945-B | 1, 4-dihydro-naphthyridine derivatives, pharmaceutical compositions and uses thereof | 江苏欧威医药有限公司 | 2017-01-18 | — | — | CN | claimed |
| CN-105481851-A | Hexahydrobenzonaphthyridine-type optically active compound and pharmaceutical use thereof | ZHAOLONG GONG | 2016-04-13 | — | — | CN | claimed |
| WO-2007028171-A9 | METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF CANCER | SUNESIS PHARMACEUTICALS, INC. (US) | 2014-12-11 | — | — | WO | claimed |
| CN-104203945-A | 1, 4-dihydro-naphthyridine derivatives, pharmaceutical compositions and uses thereof | JIANGSU SIMOVAY PHARMACEUTICAL CO LTD | 2014-12-10 | — | — | CN | claimed |
| CN-103889414-A | pharmaceutical composition | RAQUALIA PHARMA INC | 2014-06-25 | — | — | CN | claimed |
| CN-102574840-B | R-7-(3-aminomethyl-4-methoxyimino-3-methyl-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid and l-aspartic acid salt, process for the preparation thereof and pharmaceutical composition comprising the same | ARMED INC | 2014-05-28 | — | — | CN | claimed |
| CN-1377347-A | Pharmaceutically active sulfonamide derivatives | APPLIED RESEARCH SYSTEMS (NL) | 2002-10-30 | — | — | CN | claimed |
| EP-1230235-A1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | New Pharma Research Sweden AB (SE) | 2002-08-14 | — | — | EP | claimed |
| WO-2001036408-A1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2001-05-25 | — | — | WO | claimed |
| CN-1257489-A | Substituted benzopyran derivatives for the treatment of inflammation | SEARLE & CO (US) | 2000-06-21 | — | — | CN | claimed |
| WO-1995007909-A1 | ALKYL-1-ALKYL-4-HYDROXY-2-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLATES AS ANTI-RHEUMATIC AGENTS | KNOLL AG (DE) | 1995-03-23 | — | — | WO | claimed |
| EP-0562042-A4 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | claimed |
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | claimed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | claimed |
| EP-0120832-B1 | 4-ALKYLINDOLONAPHTHYRIDINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | OMNICHEM Société anonyme (BE) | 1987-04-29 | — | — | EP | claimed |
| EP-0120832-A1 | 4-Alkylindolonaphthyridines and pharmaceutical compositions containing them | OMNICHEM Société anonyme (BE) | 1984-10-03 | — | — | EP | claimed |