Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 7/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | STAMBP | O95630 | 6/20 | 0.42 |
| ▸ | COPS5 | Q92905 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124592 | 0.86 | MGAM (0.59) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| SCHEMBL30392839 | 0.86 | MGAM (0.59) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| Hydrochloric Acid SCHEMBL7010614 | 0.84 | MGAM (0.57) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| Hydrochloric Acid SCHEMBL9378228 | 0.84 | MGAM (0.57) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| Water SCHEMBL8227338 | 0.77 | ACP1 (0.51) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| SCHEMBL27501111 | 0.73 | MGAM (0.79) | PSMD14MGAMMEN1KMT2ALMNA | |
| SCHEMBL163182 | 0.72 | PSMD14 (0.56) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| Aspartic Acid SCHEMBL27878589 | 0.72 | MGAM (0.43) | PSMD14MGAMMEN1KMT2ALMNA | |
| SCHEMBL21358078 | 0.71 | PSMD14 (0.60) | PSMD14MGAMSTAMBPCOPS5MEN1 | |
| Hydrochloric Acid SCHEMBL14966721 | 0.71 | PSMD14 (0.55) | PSMD14MGAMSTAMBPCOPS5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104688732-A | Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity | SUNESIS PHARMACEUTICALS INC | 2015-06-10 | — | — | CN | disclosed |