Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPID | Q08752 | 2/20 | 0.41 |
| ▸ | PPIG | Q13427 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28196542 | 0.85 | HPGD (0.57) | ALDH1A1LMNAHPGDKMT2AMEN1 | |
| SCHEMBL8269170 | 0.81 | ALDH1A1 (0.44) | PPIBALDH1A1PPIDPPIGLMNA | |
| SCHEMBL4052270 | 0.81 | NUDT1 (0.49) | PPIBALDH1A1PPIDPPIGLMNA | |
| SCHEMBL17084616 | 0.80 | MAPT (0.58) | ALDH1A1LMNACNR2KMT2AGLS | |
| SCHEMBL780470 | 0.78 | HPGD (0.49) | PPIBALDH1A1PPIDPPIGLMNA | |
| SCHEMBL5582645 | 0.77 | HDAC1 (0.49) | HDAC1ALDH1A1LMNACNR2HPGD | |
| SCHEMBL13101015 | 0.77 | HPGD (0.47) | PPIBALDH1A1PPIDPPIGLMNA | |
| SCHEMBL18868428 | 0.75 | ALDH1A1 (0.61) | HDAC1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL12460089 | 0.75 | HPGD (0.51) | HDAC1LMNAHPGDKMT2ARAB9A | |
| SCHEMBL1578976 | 0.75 | PPIB (0.46) | PPIBALDH1A1PPIDPPIGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343303-A1 | PI3-kinase inhibitors | Boehringer Ingelheim International GmbH (DE) | 2011-07-13 | — | — | EP | disclosed |