SCHEMBL1246046

SCHEMBL1246046

O=C(OCCO)c1ccccc1C(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.57
ALDH1A1 P00352 5/20 0.57
CYP3A4 P08684 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
AKR1C3 P42330 1/20 0.53
TSHR P16473 5/20 0.51
GAA P10253 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
TP53 P04637 1/20 0.49
MAPK1 P28482 1/20 0.49
LMNA P02545 2/20 0.47
PKM P14618 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11985680 0.91 ALDH1A1 (0.62) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL14594371 0.88 TDP1 (0.67) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL22361800 0.87 ALDH1A1 (0.58) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL36533 0.87 ALDH1A1 (0.67) L3MBTL1ALDH1A1CYP3A4TSHRTDP1
SCHEMBL11985705 0.86 ALDH1A1 (0.65) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL22373554 0.86 ALDH1A1 (0.51) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
Benzophenone SCHEMBL28261937 0.85 TDP1 (0.63) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL30749815 0.85 ALDH1A1 (0.64) L3MBTL1ALDH1A1CYP3A4TSHRTDP1
SCHEMBL21567537 0.85 ALDH1A1 (0.77) L3MBTL1ALDH1A1CYP3A4CYP1A2CYP2C9
SCHEMBL29668022 0.84 ALDH1A1 (0.62) L3MBTL1ALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11414557-B2 Active-energy-ray-polymerizable initiator, active-energy-ray-polymerizable composition, active-energy-ray-polymerizable ink, ink storage container, image forming method, and image forming apparatus RICOH COMPANY, LTD. (JP) 2022-08-16 US disclosed
US-20200270469-A1 ACTIVE-ENERGY-RAY-POLYMERIZABLE INITIATOR, ACTIVE-ENERGY-RAY-POLYMERIZABLE COMPOSITION, ACTIVE-ENERGY-RAY-POLYMERIZABLE INK, INK STORAGE CONTAINER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2020-08-27 US disclosed
EP-2394676-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2018-03-28 EP disclosed
EP-2459242-B1 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST AS (DK) 2015-10-21 EP disclosed
EP-2104523-B1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST AS (DK) 2015-08-26 EP disclosed
US-8932662-B2 Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds COLOPLAST A/S (DK) 2015-01-13 US disclosed
EP-2459242-A2 A MEDICAL DEVICE OF POLYOLEFIN Coloplast A/S (DK) 2012-06-06 EP disclosed
US-20120121919-A1 MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2012-05-17 US disclosed
WO-2011012137-A2 A MEDICAL DEVICE OF POLYOLEFIN COLOPLAST A/S (DK) 2011-02-03 WO disclosed
US-20100049146-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2010-02-25 US disclosed
EP-2104523-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS Coloplast A/S (DK) 2009-09-30 EP disclosed
WO-2008071796-A1 COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS COLOPLAST A/S (DK) 2008-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11414557-B2 Active-energy-ray-polymerizable initiator, active-energy-ray-polymerizable composition, active-energy-ray-polymerizable ink, ink storage container, image forming method, and image forming apparatus ILK, NAP1L4, ORC3 L3MBTL1 51/4885ALDH1A1 1527/4885CYP3A4 3270/4885
US-20200270469-A1 ACTIVE-ENERGY-RAY-POLYMERIZABLE INITIATOR, ACTIVE-ENERGY-RAY-POLYMERIZABLE COMPOSITION, ACTIVE-ENERGY-RAY-POLYMERIZABLE INK, INK STORAGE CONTAINER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS ILK, NAP1L4, ORC3 L3MBTL1 51/4885ALDH1A1 1527/4885CYP3A4 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.