SCHEMBL146170

SCHEMBL146170

O=C(OCC1CC2C=CC1C2)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
THRB P10828 1/20 0.32
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12634106 0.87 KDM4E (0.30) KDM4EALDH1A1TDP1
SCHEMBL13237650 0.85 KDM4E (0.31) KDM4EALDH1A1TDP1
SCHEMBL12634108 0.83 KDM4E (0.30) KDM4E
SCHEMBL13237655 0.83 KDM4E (0.33) KDM4EALDH1A1TDP1
SCHEMBL24142269 0.82 KDM4E (0.33) KDM4EALDH1A1TDP1PKM
SCHEMBL12460487 0.81 KDM4E (0.31) KDM4E
SCHEMBL25689244 0.80 KDM4E (0.36) KDM4EALDH1A1TDP1PKM
SCHEMBL22883585 0.80 KDM4E (0.36) KDM4EALDH1A1TDP1PKM
SCHEMBL12128652 0.80 KDM4E (0.36) KDM4EALDH1A1TDP1PKM
SCHEMBL12922446 0.78 KDM4E (0.33) KDM4EALDH1A1TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018148479-A1 PHOTOALIGNMENT FILM FORMING COMPOSITION AND LCD DEVICES DERIVED THEREFROM PROMERUS, LLC (US) 2018-08-16 WO claimed
US-10591818-B2 Nadic anhydride polymers and photosensitive compositions derived therefrom PROMERUS, LLC (US) 2020-03-17 US disclosed
US-10429734-B2 Permanent dielectric compositions containing photoacid generator and base PROMERUS, LLC (US) 2019-10-01 US disclosed
US-10054854-B2 Fluorine free photopatternable phenol functional group containing polymer compositions PROMERUS, LLC (US) 2018-08-21 US disclosed
US-20180030189-A1 NADIC ANHYDRIDE POLYMERS AND PHOTOSENSITIVE COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-02-01 US disclosed
US-20170153546-A1 PERMANENT DIELECTRIC COMPOSITIONS CONTAINING PHOTOACID GENERATOR AND BASE PROMERUS, LLC (US) 2017-06-01 US disclosed
US-9647222-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9647213-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-20170097566-A1 FLUORINE FREE PHOTOPATTERNABLE PHENOL FUNCTIONAL GROUP CONTAINING POLYMER COMPOSITIONS SUMITOMO BAKELITE CO., LTD. (JP) 2017-04-06 US disclosed
US-9583713-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
EP-2676978-A1 Interlayer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2676979-A1 Gate insulator layer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2611842-A1 INTERLAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
EP-2611841-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
US-20120056249-A1 INTERLAYER FOR ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
WO-2012028278-A1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
WO-2012028279-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
US-20120056183-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
EP-1853972-B1 NORBORNENE-TYPE POLYMERS AND THEIR MANUFACTURE PROCESS PROMERUS LLC (US) 2011-07-20 EP disclosed
WO-2008121804-A1 USE OF A COMBINATION CHAIN TRANSFER AND ACTIVATING AGENT TO CONTROL MOLECULAR WEIGHT AND OPTICAL DENSITY OF PD CATALYZED NORBORNENE POLYMERS PROMERUS LLC (US) 2008-10-09 WO disclosed