Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.51 |
| ▸ | AR | P10275 | 4/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.51 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14553142 | 0.85 | PGR (0.49) | PGRARNR3C1NR3C2ELOVL6 | |
| SCHEMBL12394684 | 0.85 | PGR (0.71) | PGRARNR3C1NR3C2ELOVL6 | |
| SCHEMBL3870526 | 0.79 | PGR (0.73) | PGRARNR3C1NR3C2 | |
| SCHEMBL3873417 | 0.78 | ELOVL6 (0.42) | PGRARNR3C1NR3C2ELOVL6 | |
| SCHEMBL10960160 | 0.73 | ELOVL6 (0.45) | PGRARNR3C1NR3C2ELOVL6 | |
| SCHEMBL4120633 | 0.73 | ELOVL6 (0.42) | PGRELOVL6 | |
| SCHEMBL10531285 | 0.73 | ELOVL6 (0.42) | PGRARNR3C1NR3C2ELOVL6 | |
| SCHEMBL3874035 | 0.72 | PGR (0.78) | PGR | |
| SCHEMBL10956566 | 0.70 | PGR (0.50) | PGRELOVL6 | |
| SCHEMBL3870838 | 0.70 | PGR (0.78) | PGRARNR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178311-A1 | Purification of Progesterone Receptor Modulators | WYETH LLC (US) | 2011-07-21 | — | — | US | disclosed |
| US-7514466-B2 | Purification of progesterone receptor modulators | WYETH (US) | 2009-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178311-A1 | Purification of Progesterone Receptor Modulators | PGR, PGRMC1, PGRMC2 | PGR 1/4885AR 54/4885NR3C1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.