Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023331 | 1.00 | HRH3 (0.57) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL8487924 | 0.98 | HRH3 (0.54) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8486073 | 0.96 | HRH3 (0.53) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL13093547 | 0.95 | HDAC1 (0.58) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL5139430 | 0.95 | HDAC1 (0.58) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL8833465 | 0.93 | MMP3 (0.57) | HRH3HDAC1HDAC2MMP3HRH2 | |
| SCHEMBL1715325 | 0.92 | HRH3 (0.53) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4382750 | 0.90 | HRH3 (0.51) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL12408526 | 0.90 | HRH3 (0.66) | HRH3HDAC1HDAC2MMP3ALDH1A1 | |
| SCHEMBL5526919 | 0.90 | HRH3 (0.66) | HRH3HDAC1HDAC2MMP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9585891-B2 | Alpha hydroxy amides | MERCK PATENT GMBH (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20150250792-A1 | ALPHA HYDROXY AMIDES | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150250792-A1 | ALPHA HYDROXY AMIDES | HCAR1, NAA40, HCAR2 | HRH3 32/4885HDAC1 252/4885HDAC2 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.