Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1715021 | 0.98 | CACNA1B (0.52) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL12461375 | 0.89 | LSS (0.50) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL492168 | 0.87 | CACNA1B (0.66) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL12461386 | 0.86 | MMP2 (0.50) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL12461916 | 0.86 | CACNA1B (0.49) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL4087894 | 0.81 | HRH3 (0.59) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL491657 | 0.81 | KDM4E (0.55) | CACNA1BKDM4EHRH3CYP19A1 | |
| SCHEMBL491881 | 0.81 | KDM4E (0.64) | CACNA1BMMP2ALDH1A1MMP3CACNA1H | |
| SCHEMBL21601511 | 0.81 | MMP2 (0.52) | CACNA1BMMP2ALDH1A1MMP3MAPT | |
| SCHEMBL491721 | 0.81 | ATP4A (0.49) | CACNA1BMMP2ALDH1A1MMP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |