Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065880 | 0.79 | MEN1 (0.70) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL1143297 | 0.79 | MEN1 (0.70) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL5505167 | 0.79 | MEN1 (1.00) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL136847 | 0.79 | MEN1 (0.70) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL1424722 | 0.79 | ALDH1A1 (1.00) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL27854840 | 0.78 | MEN1 (0.71) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL1365078 | 0.75 | RAB9A (0.72) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL8289685 | 0.75 | RAB9A (0.64) | MEN1KMT2ARAB9AALDH1A1USP2 | |
| SCHEMBL6852409 | 0.73 | ALDH1A1 (0.68) | ALDH1A1LMNAHSD17B10MAPTHTT | |
| SCHEMBL15453216 | 0.72 | ALDH1A1 (0.47) | RAB9AALDH1A1LMNAGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343286-A1 | Dibenzo[b,f][1,4]oxazepine derivatives as inhibitors of histone deacetylase | Methylgene, Inc. (CA) | 2011-07-13 | — | — | EP | disclosed |