Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.85 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.82 |
| ▸ | F2 | P00734 | 2/20 | 0.82 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.82 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.82 |
| ▸ | PLAU | P00749 | 1/20 | 0.82 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.82 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.82 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.82 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.82 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.82 |
| ▸ | F10 | P00742 | 1/20 | 0.82 |
| ▸ | PLG | P00747 | 1/20 | 0.82 |
| ▸ | S100B | P04271 | 1/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.82 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.82 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.82 |
| ▸ | AOC1 | P19801 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12461521 | 0.98 | PRMT1 (0.86) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL12460727 | 0.98 | PRMT1 (0.86) | PRSS1PRMT1F2ST14TMPRSS2 | |
| Hydrochloric Acid SCHEMBL1715174 | 0.98 | PRSS1 (0.86) | PRSS1PRMT1F2ST14TMPRSS2 | |
| Hydrochloric Acid SCHEMBL1715183 | 0.96 | PRSS1 (0.86) | PRSS1PRMT1F2ST14TMPRSS2 | |
| Hydrochloric Acid SCHEMBL1715428 | 0.96 | PRSS1 (0.86) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL12460728 | 0.94 | PRSS1 (0.81) | PRSS1PRMT1F2ST14TMPRSS2 | |
| Hydrochloric Acid SCHEMBL1714481 | 0.93 | PRSS1 (0.82) | PRSS1PRMT1F2ST14TMPRSS2 | |
| SCHEMBL6408670 | 0.92 | PRSS1 (1.00) | PRSS1PRMT1F2ST14TMPRSS2 | |
| Heptamidine SCHEMBL14599630 | 0.90 | PRMT1 (1.00) | PRSS1PRMT1F2ST14TMPRSS2 | |
| Hexamidine SCHEMBL144738 | 0.90 | PRMT1 (1.00) | PRSS1PRMT1F2ST14TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481966-B1 | NOVEL ARYLAMIDINE DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |