Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14462481 | 0.75 | PIK3CA (0.53) | KCNH2 | |
| SCHEMBL18171776 | 0.72 | GABRA1 (0.41) | NPC1RAB9AALDH1A1MAPTATM | |
| SCHEMBL2492257 | 0.69 | KDM4E (0.48) | NPC1RAB9AALDH1A1MAPTATM | |
| Bromide SCHEMBL2724184 | 0.68 | KDM4E (0.46) | NPC1RAB9AALDH1A1MAPTATM | |
| SCHEMBL15842989 | 0.66 | NISCH (0.46) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL21664141 | 0.66 | LMNA (0.34) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL21663873 | 0.66 | SMN1; SMN2 (0.34) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL21664135 | 0.66 | KDM4E (0.49) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL21663821 | 0.65 | SMN1; SMN2 (0.35) | NPC1RAB9AALDH1A1MAPTATM | |
| SCHEMBL2391963 | 0.64 | GABRA1 (0.35) | NPC1RAB9AMAPTATMGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |