Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13409345 | 0.89 | MAPT (0.42) | KDM4EALDH1A1MAPTL3MBTL1CASP1 | |
| SCHEMBL8272618 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1MAPTL3MBTL1CASP1 | |
| SCHEMBL1536493 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1MAPTL3MBTL1CASP1 | |
| SCHEMBL1536660 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1MAPTL3MBTL1CASP1 | |
| SCHEMBL13444511 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTCASP7HSD17B10 | |
| SCHEMBL13763566 | 0.80 | IDH1 (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL12463992 | 0.80 | NPC1 (0.48) | KDM4EALDH1A1MAPTHSD17B10MAPK1 | |
| SCHEMBL8300158 | 0.79 | NPC1 (0.59) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL14801186 | 0.78 | MAPT (0.56) | KDM4EALDH1A1MAPTL3MBTL1CASP1 | |
| SCHEMBL8621142 | 0.78 | MAPT (0.56) | KDM4EALDH1A1MAPTL3MBTL1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |