SCHEMBL8621142

SCHEMBL8621142

CCN(CC)c1ccc(-c2cc(-c3ccc(OC)cc3)cc(-c3ccc(N(CC)CC)cc3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
MAPK1 P28482 3/20 0.56
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
KDM4E B2RXH2 2/20 0.56
HPGD P15428 1/20 0.56
TSHR P16473 1/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ADORA3 P0DMS8 2/20 0.48
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
MCL1 Q07820 2/20 0.46
DYRK1A Q13627 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14801186 1.00 MAPT (0.56) MAPTMAPK1ALDH1A1LMNATDP1
SCHEMBL14801996 0.94 KDM4E (0.51) MAPTMAPK1ALDH1A1LMNATDP1
SCHEMBL14819125 0.87 LMNA (0.48) MAPTMAPK1ALDH1A1LMNATDP1
SCHEMBL7859483 0.83 ADORA3 (0.61) MAPTMAPK1ALDH1A1LMNAKDM4E
SCHEMBL8623343 0.83 LTB4R (0.43) MAPTMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL14805217 0.83 MEN1 (0.47) MAPTMAPK1ALDH1A1LMNATDP1
SCHEMBL8616876 0.83 MEN1 (0.47) MAPTMAPK1ALDH1A1LMNATDP1
SCHEMBL9013944 0.83 KMT2A (0.47) MAPTMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL10661566 0.83 KMT2A (0.47) MAPTMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL8616869 0.83 KDM4E (0.55) MAPTALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
EP-0061128-B1 PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM STERLING DRUG INC. (US) 1985-09-04 EP disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed
US-4363503-A FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS STERLING DRUG INC. (US) 1982-12-14 US disclosed
EP-0061128-A1 Pyridine compounds, process for their preparation and systems containing them STERLING DRUG INC. (US) 1982-09-29 EP disclosed