Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464471 | 0.92 | CTSC (0.51) | CTSCECE1PSMB8PSMB9 | |
| SCHEMBL12464194 | 0.89 | CTSC (0.67) | CTSCECE1 | |
| SCHEMBL12464198 | 0.83 | MC5R (0.59) | — | |
| SCHEMBL12464202 | 0.83 | MC5R (0.59) | — | |
| SCHEMBL12464481 | 0.83 | MC5R (0.59) | — | |
| SCHEMBL12464203 | 0.82 | — | — | |
| SCHEMBL12464474 | 0.81 | CTSC (0.58) | CTSC | |
| SCHEMBL12464482 | 0.79 | MC5R (0.54) | — | |
| SCHEMBL12464363 | 0.78 | — | — | |
| SCHEMBL12464361 | 0.78 | CTSC (0.53) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |